目的：开发和验证一种自动化方法，用于对新生儿重症监护病房中睡眠状态波动的床旁监测。方法：基于深度学习的算法是使用30个近期新生儿的长期（a）脑电图监测的53个EEG录音设计和训练的。使用来自30个多摄影记录的外部数据集对结果进行了验证。除了训练和验证单个脑电图通道安静的睡眠探测器外，我们还构建了睡眠状态趋势（SST），这是一种可视化分类器输出的床旁准备手段。结果：训练数据中安静的睡眠检测的准确性为90％，在4电极记录中获得的所有双极派生中，精度是可比的（85-86％）。该算法很好地概括了外部数据集，尽管信号推导不同，但仍显示81％的总体精度。 SST允许对分类器输出的直观，清晰可视化。结论：可以从单个EEG通道的高保真度中检测到睡眠状态的波动，并且可以将结果可视化为床边监视器中透明和直观的趋势。意义：睡眠状态趋势（SST）可以为护理人员提供对睡眠状态波动及其周期性的实时视图。

由于数据保护法和机构内的官方程序，在实践中很难在机构之间共享医疗数据。因此，大多数现有的算法经过相对较小的脑电图（EEG）数据集的培训，这可能会损害预测准确性。在这项工作中，我们通过将公开可用的数据集分配到代表各个机构中数据的不相交集中来共享数据时模拟了一个情况。我们建议在每个机构中培训一个（本地）检测器，并将其个人预测汇总为最终预测。比较了四个集合计划，即多数投票，平均值，加权平均值和Dawid-Skene方法。该方法仅使用EEG通道的一个子集在独立的数据集上进行了验证。当每个机构提供足够数量的数据时，合奏的精度与对所有数据进行训练的单个检测器相当。加权平均聚合方案表现出最佳性能，当局部检测器接近对所有可用数据训练的单个检测器的性能时，它只能用DAWID-SKENE方法略有优于。

Compliance in actuation has been exploited to generate highly dynamic maneuvers such as throwing that take advantage of the potential energy stored in joint springs. However, the energy storage and release could not be well-timed yet. On the contrary, for multi-link systems, the natural system dynamics might even work against the actual goal. With the introduction of variable stiffness actuators, this problem has been partially addressed. With a suitable optimal control strategy, the approximate decoupling of the motor from the link can be achieved to maximize the energy transfer into the distal link prior to launch. However, such continuous stiffness variation is complex and typically leads to oscillatory swing-up motions instead of clear launch sequences. To circumvent this issue, we investigate decoupling for speed maximization with a dedicated novel actuator concept denoted Bi-Stiffness Actuation. With this, it is possible to fully decouple the link from the joint mechanism by a switch-and-hold clutch and simultaneously keep the elastic energy stored. We show that with this novel paradigm, it is not only possible to reach the same optimal performance as with power-equivalent variable stiffness actuation, but even directly control the energy transfer timing. This is a major step forward compared to previous optimal control approaches, which rely on optimizing the full time-series control input.

Recent advances in deep learning have enabled us to address the curse of dimensionality (COD) by solving problems in higher dimensions. A subset of such approaches of addressing the COD has led us to solving high-dimensional PDEs. This has resulted in opening doors to solving a variety of real-world problems ranging from mathematical finance to stochastic control for industrial applications. Although feasible, these deep learning methods are still constrained by training time and memory. Tackling these shortcomings, Tensor Neural Networks (TNN) demonstrate that they can provide significant parameter savings while attaining the same accuracy as compared to the classical Dense Neural Network (DNN). In addition, we also show how TNN can be trained faster than DNN for the same accuracy. Besides TNN, we also introduce Tensor Network Initializer (TNN Init), a weight initialization scheme that leads to faster convergence with smaller variance for an equivalent parameter count as compared to a DNN. We benchmark TNN and TNN Init by applying them to solve the parabolic PDE associated with the Heston model, which is widely used in financial pricing theory.

In a sequential decision-making problem, having a structural dependency amongst the reward distributions associated with the arms makes it challenging to identify a subset of alternatives that guarantees the optimal collective outcome. Thus, besides individual actions' reward, learning the causal relations is essential to improve the decision-making strategy. To solve the two-fold learning problem described above, we develop the 'combinatorial semi-bandit framework with causally related rewards', where we model the causal relations by a directed graph in a stationary structural equation model. The nodal observation in the graph signal comprises the corresponding base arm's instantaneous reward and an additional term resulting from the causal influences of other base arms' rewards. The objective is to maximize the long-term average payoff, which is a linear function of the base arms' rewards and depends strongly on the network topology. To achieve this objective, we propose a policy that determines the causal relations by learning the network's topology and simultaneously exploits this knowledge to optimize the decision-making process. We establish a sublinear regret bound for the proposed algorithm. Numerical experiments using synthetic and real-world datasets demonstrate the superior performance of our proposed method compared to several benchmarks.

An oft-cited open problem of federated learning is the existence of data heterogeneity at the clients. One pathway to understanding the drastic accuracy drop in federated learning is by scrutinizing the behavior of the clients' deep models on data with different levels of "difficulty", which has been left unaddressed. In this paper, we investigate a different and rarely studied dimension of FL: ordered learning. Specifically, we aim to investigate how ordered learning principles can contribute to alleviating the heterogeneity effects in FL. We present theoretical analysis and conduct extensive empirical studies on the efficacy of orderings spanning three kinds of learning: curriculum, anti-curriculum, and random curriculum. We find that curriculum learning largely alleviates non-IIDness. Interestingly, the more disparate the data distributions across clients the more they benefit from ordered learning. We provide analysis explaining this phenomenon, specifically indicating how curriculum training appears to make the objective landscape progressively less convex, suggesting fast converging iterations at the beginning of the training procedure. We derive quantitative results of convergence for both convex and nonconvex objectives by modeling the curriculum training on federated devices as local SGD with locally biased stochastic gradients. Also, inspired by ordered learning, we propose a novel client selection technique that benefits from the real-world disparity in the clients. Our proposed approach to client selection has a synergic effect when applied together with ordered learning in FL.

Remote state estimation of large-scale distributed dynamic processes plays an important role in Industry 4.0 applications. In this paper, we focus on the transmission scheduling problem of a remote estimation system. First, we derive some structural properties of the optimal sensor scheduling policy over fading channels. Then, building on these theoretical guidelines, we develop a structure-enhanced deep reinforcement learning (DRL) framework for optimal scheduling of the system to achieve the minimum overall estimation mean-square error (MSE). In particular, we propose a structure-enhanced action selection method, which tends to select actions that obey the policy structure. This explores the action space more effectively and enhances the learning efficiency of DRL agents. Furthermore, we introduce a structure-enhanced loss function to add penalties to actions that do not follow the policy structure. The new loss function guides the DRL to converge to the optimal policy structure quickly. Our numerical experiments illustrate that the proposed structure-enhanced DRL algorithms can save the training time by 50% and reduce the remote estimation MSE by 10% to 25% when compared to benchmark DRL algorithms. In addition, we show that the derived structural properties exist in a wide range of dynamic scheduling problems that go beyond remote state estimation.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

In this paper, we perform an exhaustive evaluation of different representations to address the intent classification problem in a Spoken Language Understanding (SLU) setup. We benchmark three types of systems to perform the SLU intent detection task: 1) text-based, 2) lattice-based, and a novel 3) multimodal approach. Our work provides a comprehensive analysis of what could be the achievable performance of different state-of-the-art SLU systems under different circumstances, e.g., automatically- vs. manually-generated transcripts. We evaluate the systems on the publicly available SLURP spoken language resource corpus. Our results indicate that using richer forms of Automatic Speech Recognition (ASR) outputs allows SLU systems to improve in comparison to the 1-best setup (4% relative improvement). However, crossmodal approaches, i.e., learning from acoustic and text embeddings, obtains performance similar to the oracle setup, and a relative improvement of 18% over the 1-best configuration. Thus, crossmodal architectures represent a good alternative to overcome the limitations of working purely automatically generated textual data.

This paper describes a simple yet efficient repetition-based modular system for speeding up air-traffic controllers (ATCos) training. E.g., a human pilot is still required in EUROCONTROL's ESCAPE lite simulator (see https://www.eurocontrol.int/simulator/escape) during ATCo training. However, this need can be substituted by an automatic system that could act as a pilot. In this paper, we aim to develop and integrate a pseudo-pilot agent into the ATCo training pipeline by merging diverse artificial intelligence (AI) powered modules. The system understands the voice communications issued by the ATCo, and, in turn, it generates a spoken prompt that follows the pilot's phraseology to the initial communication. Our system mainly relies on open-source AI tools and air traffic control (ATC) databases, thus, proving its simplicity and ease of replicability. The overall pipeline is composed of the following: (1) a submodule that receives and pre-processes the input stream of raw audio, (2) an automatic speech recognition (ASR) system that transforms audio into a sequence of words; (3) a high-level ATC-related entity parser, which extracts relevant information from the communication, i.e., callsigns and commands, and finally, (4) a speech synthesizer submodule that generates responses based on the high-level ATC entities previously extracted. Overall, we show that this system could pave the way toward developing a real proof-of-concept pseudo-pilot system. Hence, speeding up the training of ATCos while drastically reducing its overall cost.